| Player | Wins |
|---|---|
| Addie Joss | 81 |
| Ed Plank | 79 |
| Christy Mathewson | 77 |
| Mordecai Brown | 69 |
| Ed Walsh | 69 |
| Jack Chesbro | 67 |
| Rube Waddell | 66 |
| Greg Maddux | 66 |
| Pete Alexander | 64 |
| Walter Johnson | 59 |
| Joe McGinnity | 58 |
| Chief Bender | 57 |
| Bob Gibson | 54 |
| Pedro Martinez | 54 |
| Sandy Koufax | 54 |
| Cy Young | 54 |
| Jim Palmer | 54 |
| Bret Saberhagen | 52 |
| Babe P. Ruth | 48 |
| Juan Marichal | 48 |
| Tom Seaver | 46 |
| Don Sutton | 43 |
| Curt Schilling | 42 |
| Nolan Ryan | 42 |
| Carl Hubbell | 41 |
| Steve Carlton | 40 |
| Bob Feller | 40 |
| Dean Chance | 39 |
| Sid Fernandez | 39 |
| Kid Nichols | 39 |