| Player | Season | Walks |
|---|---|---|
| Babe Ruth (NOH) | 1 | 186 |
| Babe Ruth (STL) | 2 | 171 |
| Babe Ruth (GRR) | 4 | 164 |
| Ted Williams (NOH) | 2 | 146 |
| Ted Williams (STL) | 1 | 145 |
| Ted Williams (PTL) | 4 | 132 |
| Lou Gehrig (VGA) | 3 | 124 |
| Ted Williams (PTL) | 3 | 123 |
| Lou Gehrig (VGA) | 4 | 120 |
| Frank Thomas (VGA) | 2 | 120 |
| Charlie Keller (VGA) | 4 | 118 |
| Babe Ruth (GRR) | 3 | 116 |
| Joe Morgan (GRR) | 4 | 115 |
| Mickey Mantle (STL) | 3 | 111 |
| Eddie Collins (VGA) | 3 | 110 |
| Lou Gehrig (SPB) | 2 | 109 |
| Ralph Kiner (SPB) | 1 | 109 |
| Joe Morgan (GRR) | 3 | 108 |
| Mickey Mantle (STL) | 1 | 107 |
| Frank Thomas (OTT) | 1 | 105 |
| Jimmie Foxx (OTT) | 2 | 104 |
| Hank Greenberg (STL) | 4 | 103 |
| Mickey Cochrane (VGA) | 4 | 100 |
| Jimmie Foxx (OTT) | 1 | 98 |
| Rickey Henderson (NOH) | 3 | 98 |
| Mel Ott (VGA) | 1 | 98 |
| Lou Gehrig (PTL) | 1 | 96 |
| Billy Hamilton (VGA) | 1 | 96 |
| Rickey Henderson (VGA) | 1 | 96 |
| Mickey Mantle (STL) | 4 | 96 |